NTTGUIDE

Cefpirome

Effect of ECMO Minimal impact on drug PK
Dose recommendation ECMO-specific dose adjustment not required
Comments, reference For P. aeruginosa, consider dosing at the higher end of the standard range, i.e., 2 gm IV (over 30 min) q8h or 2 gm IV (over 4 hr) q12h. Ref: Clin Pharmacokinet 2026;65:193.

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