Daptomycin
| Recommendation | Adjusted BW suggested |
|---|---|
| Comments | Clearance and Vd do not scale proportionally as body wt increases. Therefore, use caution at extremes of weight, even when dosing with adjusted BW (Pharmacotherapy 2023;43:226). Adjusted BW = Ideal BW + 0.4 x (Actual BW – Ideal BW). |