Recommendation	No dose adjustment appears necessary
Comments	Data from 13 obese patients; variability in study findings renders conclusion uncertain. Refs: Antimicrob Agents Chemother 2011;55:3240; J Antimicrob Chemother 2011;66:1653. A PK study (requiring clinical validation) in patients with BMI ≥40 kg/m² suggests that higher doses may be necessary to achieve adequate drug exposure (Clin Pharmacokinet 53:753, 2014).