Voriconazole

Recommendation	Use ideal BW
Comments	Dosing using actual body weight may result in supratherapeutic concentrations, but published data are insufficient to recommend adjusted BW vs. ideal BW. Best approach for now is to use ideal BW and check serum concentrations to avoid underdosing (Antimicrob Agents Chemother 55:2601, 2011; Clin Infect Dis 53:745, 2011; Clin Infect Dis 63:286, 2016; Antimicrobial Agents Chemother 2021;65:e02460-20).

Recommendation

Use ideal BW

Comments

Dosing using actual body weight may result in supratherapeutic concentrations, but published data are insufficient to recommend adjusted BW vs. ideal BW. Best approach for now is to use ideal BW and check serum concentrations to avoid underdosing (Antimicrob Agents Chemother 55:2601, 2011; Clin Infect Dis 53:745, 2011; Clin Infect Dis 63:286, 2016; Antimicrobial Agents Chemother 2021;65:e02460-20).