Ceftazidime-avibactam

Dose (Age >28 Days)	FDA-approved dosing: Age ≤28 days, GA ≥31 wks: 25 mg/kg q8h Age >28 days to <3 mon: 37.5 mg/kg q8h Age 3 mon to <6 mon: 50 mg/kg q8h Age 6 mon to <2 yrs: 62.5 mg/kg q8h Age 2 to <18 yrs: 62.5 mg/kg q8h Per AMR gram-negative guidance: Age ≤28 days, GA ≥31 wks: 31.25 mg/kg q8h Age >28 days to <3 mon: 37.5 mg/kg (over 3 hr) q8h Age 3 mon to 18 yrs: 62.5 mg/kg (over 3 hr) q8h NOTE: use 2 hour infusions for CNS infections
Max/Day	7.5 gm

Dose (Age >28 Days)

FDA-approved dosing:
Age ≤28 days, GA ≥31 wks: 25 mg/kg q8h
Age >28 days to <3 mon: 37.5 mg/kg q8h
Age 3 mon to <6 mon: 50 mg/kg q8h
Age 6 mon to <2 yrs: 62.5 mg/kg q8h
Age 2 to <18 yrs: 62.5 mg/kg q8h
Per AMR gram-negative guidance:
Age ≤28 days, GA ≥31 wks: 31.25 mg/kg q8h
Age >28 days to <3 mon: 37.5 mg/kg (over 3 hr) q8h
Age 3 mon to 18 yrs: 62.5 mg/kg (over 3 hr) q8h
NOTE: use 2 hour infusions for CNS infections

Max/Day

7.5 gm