Amikacin
| PK/PD Index | 24-hr AUC/MIC |
|---|---|
| Pharmaceutical Preparations | Injection, liposome inhalation susp |
| Food Rec (PO Drugs) 1 | - |
| Oral Absorption (%) | - |
| Tmax (hr) | - |
| Peak Serum Conc (µg/mL) 2 | 41-49 (15 mg/kg IV, SD) |
| Peak Urine Conc (µg/mL) | No data |
| Protein Binding (%) | 0-10 |
| Volume of Distribution (Vd) 3 | 0.26 L/kg |
| Avg Serum T½ (hr) 4 | 2-3 |
| Elimination | Renal |
| Bile Penetration (%) 5 | 10-60 |
| CSF/blood (%) 6 | 0-30 |
| Therapeutic Levels in CSF 7 | No |
| AUC (µg*hr/mL) 8 | 110-145 (15 mg/kg, 0-inf) |