NTTGUIDE

Plazomicin

PK/PD Index 24-hr AUC/MIC
Pharmaceutical Preparations Injection
Food Rec (PO Drugs) 1 -
Oral Absorption (%) -
Tmax (hr) -
Peak Serum Conc (µg/mL) 2 51-74 (15 mg/kg IV, SD)
Peak Urine Conc (µg/mL) No data
Protein Binding (%) 20
Volume of Distribution (Vd) 3 18-31 L
Avg Serum T½ (hr) 4 3.5
Elimination Renal
Bile Penetration (%) 5 No data
CSF/blood (%) 6 No data
Therapeutic Levels in CSF 7 No data
AUC (µg*hr/mL) 8 226-257 (15 mg/kg, 0-inf)

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