Acyclovir

Half-life bình thường 2.5-3.5
Half-life ESRD 20
Liều bình thường 5-12.5 mg/kg IV q8h
800 mg po q4h (5x/day)
Chỉnh liều suy thận IV:
CrCl >50: No dosage adjustment
CrCl 10-50: 5-12.5 mg/kg IV q12-24h
CrCl <10: 2.5-6.25 mg/kg IV q24h
Oral:
CrCl >25: No dosage adjustment
CrCl 10-25: 800 mg po q8h
CrCl <10: 800 mg po q12h
Hemodialysis IV:
2.5-6.25 mg/kg IV q24h
(dose AD on dialysis days)
Oral:
800 mg po q12h
(give extra dose AD)
CAPD IV:
2.5-6.25 mg/kg IV q24h
Oral:
800 mg po q12h
CRRT IV:
2.5-6.25 mg/kg IV q24h
Oral:
No data
SLED No data
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