Amoxicillin-clavulanate
| Half-life bình thường | Amoxicillin: 1.4 Clavulanate: 1 |
|---|---|
| Half-life ESRD | Amoxicillin: 5–20 Clavulanate: 4 |
| Liều bình thường | 500 mg po q8h (4:1) 875 mg po q12h (7:1) 1 gm IV q8h (5:1) |
| Chỉnh liều suy thận | Oral: CrCl >30: No dosage adjustment CrCl 10–30: 250–500 mg q12h CrCl <10: 250–500 mg q24h IV: CrCl >30: No dosage adjustment CrCl 10–30: 1 gm x1, then 500 mg q12h CrCl <10: 1 gm x1, then 500 mg q24h |
| Hemodialysis | Oral: 250–500 mg q24h (+ extra dose AD) IV: 1 gm x1, then 500 mg q24h (+ extra dose AD) |
| CAPD | No data |
| CRRT | No data |
| SLED | No data |