NTTGUIDE

Ceftazidime-avibactam

Half-life bình thường Ceftazidime 2.8
Avibactam 2.7
Half-life ESRD Ceftazidime 13–25
Liều bình thường 2.5 gm IV q8h
Chỉnh liều suy thận CrCl >50: No dosage adjustment
CrCl 31–50: 1.25 gm q8h
CrCl 16–30: 0.94 gm q12h
CrCl 6–15 (± HD): 0.94 gm q24h
CrCl ≤5 (± HD): 0.94 gm q48h
Hemodialysis 0.94 gm q24–48h
(AD on dialysis days)
CAPD No data
CRRT CVVH: 1.25 gm q8h
CVVHDF: 2.5 gm q8h
SLED No data

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