Half-life bình thường	3–4
Half-life ESRD	6–9
Liều bình thường	Varies with formulation and indication
Chỉnh liều suy thận	Tablets (non-ER): CrCl >50: No dosage adjustment CrCl 30–50: 250–500 mg q12h CrCl 5–29: 250–500 mg q18h Tablets (ER), uncomplicated UTI: No dosage adjustment Tablets (ER), cUTI and acute pyelo: CrCl >30: No dosage adjustment CrCl ≤30: 500 mg q24h Injection: CrCl ≥30: No dosage adjustment CrCl 5–29: 200–400 mg q18–24h
Hemodialysis	Tablets (non-ER): 250–500 mg q24h (AD on dialysis days) Tablets (ER), cUTI and acute pyelo: 500 mg q24h (AD on dialysis days) Injection: 200–400 mg q24h (AD on dialysis days)
CAPD	Tablets (non-ER): 250–500 mg q24h Tablets (ER), cUTI and acute pyelo: 500 mg q24h Injection: 200–400 mg q24h
CRRT	Tablets (non-ER): 250–500 mg q12h Tablets (ER), uncomplicated UTI: 500 mg q24h Tablets (ER), cUTI and acute pyelo: No data Injection: 200–400 mg q12h
SLED	No data