Half-life bình thường	2.0
Half-life ESRD	50
Liều bình thường	Varies with indication
Chỉnh liều suy thận	Shown in % of normal daily dose. Loading dose: increase first dose by 100% (max 8 gm). CrCl >40: No dosage adjustment CrCl >30 to 40: 70% (divided q8–12h) CrCl >20 to 30: 60% (divided q8–12h) CrCl >10 to 20: 40% (divided q8–12h) CrCl ≤10: 20% (divided q12–24h)
Hemodialysis	2 gm q48h (give AD)
CAPD	No data
CRRT	CVVH: No dosage adjustment (based on limited data)
SLED	5 gm q8h; another study recommends 8 gm load, then 5 gm post-SLED.³⁰