Half-life bình thường	2-3
Half-life ESRD	30-70
Liều bình thường	G- (conventional): 1.7-2.0 mg/kg IV q8h G+ (synergy): 1 mg/kg IV q8h
Chỉnh liều suy thận	G- (conventional): CrCl >50: No dosage adjustment CrCl 10-50: 1.7-2.0 mg/kg q12-24h CrCl <10: 1.7-2.0 mg /kg q48h G+ (synergy): CrCl ≥60: No dosage adjustment CrCl 40-59: 1 mg/kg q12h CrCl 20-39: 1 mg/kg q24h CrCl <20: 1 mg/kg, then dose by level
Hemodialysis	G- (conventional): 1.7-2.0 mg/kg q48h (+ extra 0.85-1.0 mg/kg AD) G+ (synergy): 1 mg/kg q48-72h (dose AD)
CAPD	For peritonitis only: 0.6 mg/kg IP once daily
CRRT	G- (conventional): 1.7-2.0 mg/kg q24h
SLED	G- (conventional): 6 mg/kg IV q48h Begin 30 min before start of SLED