NTTGUIDE

Imipenem-cilastatin-relebactam

Half-life bình thường Imipenem: 1
Half-life ESRD Imipenem: 4
Liều bình thường 1.25 gm IV q6h
Chỉnh liều suy thận CrCl ≥90: No dosage adjustment
CrCl 60-89: 1 gm q6h
CrCl 30-59: 0.75 gm q6h
CrCl 15-29: 0.5 gm q6h
CrCl <15: Not recommended
Hemodialysis 0.5 gm q6h (AD on dialysis days)
CAPD No data
CRRT No data
SLED No data

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