NTTGUIDE

Metronidazole

Half-life bình thường 6–14
Half-life ESRD 7–21
Liều bình thường 500 mg IV/po q6h
Chỉnh liều suy thận CrCl ≥10: no dosage adjustment
CrCl <10: 500 mg q12h
Hemodialysis 500 mg q12h (dose AD)
CAPD No dosage adjustment
CRRT No dosage adjustment
SLED 500 mg q12h
(1 dose immediately post-SLED)79

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