Half-life bình thường	70–100
Half-life ESRD	up to 230
Liều bình thường	See Adult Dose
Chỉnh liều suy thận	If target trough 15–30 µg/mL: Loading dose: eGFR >60: No dosage adjustment eGFR 30–60: Day 1: 12 mg/kg q12h Day 2: 10 mg/kg x1 Day 3: 6–6.7 mg/kg x1 eGFR <30: Day 1: 12 mg/kg q12h Day 2: 5 mg/kg x1 Day 3: 5 mg/kg x1 Maintenance dose: eGFR >60: No dosage adjustment eGFR 30–60: 3–3.3 mg/kg q24h eGFR <30: 5 mg/kg q48h If target trough 20–40 µg/mL: Loading dose: eGFR >60: No dosage adjustment eGFR 30–60: Day 1: 12 mg/kg q12h Day 2: 12 mg/kg x1 Day 3: 12 mg/kg x1 eGFR <30: Day 1: 12 mg/kg q12h Day 2: 12 mg/kg x1 Day 3: 6–6.7 mg/kg x1 Maintenance dose: eGFR >60: No dosage adjustment eGFR 30–60: 5 mg/kg q24h eGFR <30: 3–3.3 mg/kg q24h
Hemodialysis	Not removed by HD (use recs for eGFR <30)
CAPD	No data
CRRT	For CVVHDF: If target trough 15–30 µg/mL: Loading dose: Day 1: 10 mg/kg q12h Day 2: 10 mg/kg x1 Day 3: 10 mg/kg x1 If target trough 20–40 µg/mL: Loading dose: Day 1: 12 mg/kg q12h Day 2: 12 mg/kg x1 Day 3: 12 mg/kg x1 Maintenance dose (both targets): 3–3.3 mg/kg q24h⁶⁵
SLED	No data