NTTGUIDE

Tobramycin

Half-life bình thường 2-3
Half-life ESRD 30-70
Liều bình thường G- (conventional):
1.7-2.0 mg/kg IV q8h
Chỉnh liều suy thận G- (conventional):
CrCl >50: No dosage adjustment
CrCl 10-50: 1.7-2.0 mg/kg q12-24h
CrCl <10: 1.7-2.0 mg /kg q48h
Hemodialysis G- (conventional):
1.7-2.0 mg/kg q48h
(+ extra 0.85-1.0 mg/kg AD)
CAPD For peritonitis only:
0.6 mg/kg IP once daily
CRRT G- (conventional):
1.7-2.0 mg/kg q24h
SLED No data

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